How do the effects differ?
I’ve done infusions and used compounded ketamine nasal spray (different than esketamine (spelling?) nasal spray you do in a dr office). The nasal spray has a much lower bioavailability than iv so the experience is a lot less intense. I tried nasal spray instead of lozenges/troches but the lozenges were easier for me and seem to have a better effect.
Got it, that makes sense. Thanks for the reply! Did you prefer the lozenges to the infusions?
I had ketamine as an anesthetic after surgery and experienced complete remission of depression, anxiety, and suicidal ideation. That effect remained for a few weeks.
I am now trying nasal ketamine (generic, not esketamine) and it helps with depression but the effect isn’t nearly as strong as the IV was for surgery (and it’s certainly a much smaller dose, too).