More depressed than ever?

Hey, have any of you had treatment and after completing, still after a month, more depressed than ever in your life when you thought you were at rock bottom before the treatment? I’m so stuck and hopeless.

U might need more frequent boosters or supplement with lozenges or both. Right now I’m on lozenges 3 times a day and infusions every two weeks…

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Yes and you aren’t alone. Ketamine made my depression better for 6 months last year but then I got worse with every treatment I took after it stopped working. I took 12 initial infusions and 2 boosters during my 6 months of being well and after I crashed, I took 9 more infusions with the hope that eventually I’d get back to where I was - it never happened. I’m seeing more posts like yours these days than I did before I took the treatments. I do not plan to ever take a ketamine infusion again…they are still considered experimental therapy for depression and now I’m starting to see why. I hope you get better - listen to your body and save the heartache (and money) if the treatments are making you worse. If you ever need someone for support, email me and I’d be happy to share my experiences with you.

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Maybe you need to call the clinic where you get treatment and let them know that you are struggling. Perhaps they can add or remove something from your treatment for you to get better results.
I wish you strength and peace. :heart:

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I just finished 6 infusions and feel worse than when I started. My provider wants me to try Spravato. I’m not sure it’s even worth trying.

Welcome Ivory…I would definitely talk to the clinic to get some feedback/suggestions. Hang in there…hugs.

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Unfortunately ketamine might not work for u :sob:. I heard if u don’t respond to the initial series that it is likely not going to work at all.

One thing I’ve read about Spravato is that it is meant to be a supplement for treatment with pill medicines. I tried alot (I thought all) pill antidepressants until I finally started responding to Effexor. Now with that & a ketamine nasal spray I’m doing pretty well. Maybe someone being treated with ketamine (infusions, sprays, or whatever) should continue to look for more traditional methods to supplement the ketamine effects.

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I am so sorry you feel that way. Fortunately I feel that it really helped me. I am not where I would really like to be but I’m definitely better than I was before I started treatments I’ve only had five treatments and keep on having a push off the sixth treatment because of other things getting in the way and the fact that I still feel pretty good especially when I look at the condition I was in before I started I just hope it sticks. I’m sorry it hasn’t worked for you but don’t give up. Have you tried TMS therapy? Do you talk to a psychologist? There are so many things that you can keep you stuck and you need to try to figure out what that is. Praying that you will find relief

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My dad has chosen to test to see whether the Ketamine worked and those infusions were a waste of money. He just screwed it up. There are some people that don’t respond. My hope is that with the right doctor all of us can get some form of help from Ketamine! Big big hugs! Hang in there!

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I’m new to ketamine and to Osmind and was going to ask a similar question. I’ve had the 6 initial iv treatments and the clinic has suggested I do two more next week and see how I feel. I did feel better after the first 4, then started to feel panicky knowing I was coming to the end of the 6. I was so worried about “what next?!” that I might have sabotaged myself a little.

I was wondering how frequently people have IV treatments and how often is too often?

I hear you, @Ivory. Best of luck. Message if you want.

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Welcome Ivory, I am at my very last stop here, at least I feel that way. I have had infusions with mostly good results. They help my PTSD, trauma so much. I have tried every type of mostly every antidepressant mood stabilizer anxiety med that I can tolerate. I only use Ketamine and it is my only hope. Some days I think that it’s not working and right now it is saving my life. Yes side affects but I laugh more and I have good days but I’m still depressed and hating it right now. Ketamine gives me hope and someday maybe it will make me free of this darkness. It is so worth it to keep pushing. Some things work well and some don’t. But during those times I hope that you find strength to hold on. Peace be with you.

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I get an infusion once a month and it seems to be doing a really good job overall. After five weeks I start to feel bad again!

The problem that I have had with infusions is the cost. I am totally resistant to antidepressants and have been having infusions off and on for the last year. I was just up and down because after the initial I can only get boosters when I can afford them. My ins.co. approved Spravato and I have been doing the nasal. So to be approved by my Ins I had to try one more antidepressant. That was a couple of months ago. I’m probably the worst that I have ever been. I stopped the nasal and antidepressant and am trying to figure this out. The infusions work really well but the long term of being able to cover the cost is unpredictable. But I knew that Ketamine was my answer the first time that I had an infusion. Spravato had too many side effects for some reason. I’m trying to decide which road to take. How are all of you coping between boosters?

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I have a fund just for ketamine. Any money I am able to get back from the insurance company I put in it. I used my stimulus last round for the fund.

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So did I.

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The problem is is when your clutch goes out of your car or your dog blows out her knee it leaves little room in the budget for those other problems!

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Yes, and my dog just blew her knee out!

I recently started switching between a depression treatment a pain treatment. Before I did that I got the depression treatments every 6 weeks.

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What is the difference between Ketamine and Spravato? Is Spravato a type of Ketamine? Or in the same drug category?

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