Hey! I recently got prescribed oral ketamine after doing about 2 years of IV infusions. I get these for chronic neuropathic pain called CRPS, but also have treatment-resistant/very severe depression. Ketamine has absolutely changed and improved my life.
You are right that IV ketamine can be very psychedelic - but the protocol for pain treatment is different than that for depression - it’s a much higher dose - 600mg/4 hours. I’ve had one bad experience, out of ~20 infusions, and the benefits outweighed the bad side effects. So you may have a psychedelic experience during the infusion, but I believe the depression is treated with a lower dose over a shorter period.
I’ve only been taking the oral for 2 days - (20mg capsules 2x daily) but I feel a very noticeable improvement in my depression. It’s wonderful honestly. Everyone is different, and I don’t know whether the brain builds a tolerance to ketamine (if so, I have a higher tolerance for sure) but I’m not finding the at-home prescription to be psychedelic at all. I’m just very slightly light-headed and grateful to have some relief from the constant pain (physical and mental).
I hope this helps, I’m happy to answer questions if you have any. Good luck to you!!